Her main research area is public health and addictions, with a focus on testing alternative approaches to expand and diversify treatments for vulnerable populations.

She is currently part of several Canadian Institutes of Health Research-funded grants; formerly co-investigator of North America’s first heroin-assisted treatment trial, the North American Opiate Medication Initiative (NAOMI); and formerly the principal investigator of the Study to Assess Long-Term Opioid Maintenance Effectiveness (SALOME), a randomized clinical trial that tested innovative treatments for severe, long-term opioid dependency. She is also the principal investigator of the GeMa (Gender Matters) study, which evaluates gender patterns of drug use, access to care, and health among long-term opioid users; a co-investigator of The Cedar Project, a cohort of young Aboriginal people using drugs; and the principal investigator of the Program of Outcomes Research on Treatment with Injectables for Addiction (PORTIA).